Article
Expression pattern of the Brachyury gene in whole-mount TWis/TWis mutant embryos.
Development (Cambridge, England) - 1 Nov 1991
Herrmann B G
Abstract excerpt
The murine Brachyury (T) gene is required in mesoderm formation. Mutants carrying different T alleles show a graded severity of defects correlated with gene dosage along the body axis. The phenotypes range from shortening of the tail to the malformation of sacral vertebrae in heterozygotes, and t...
Topics
- Animals
- Embryo, Mammalian
- Gene Expression
- Genes
- Genotype
- Mesoderm
- Mice
- Mice, Mutant Strains
- Microscopy, Electron
- Molecular Probe Techniques
- Morphogenesis
- Mutation
- Phenotype