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Article

Expression pattern of the Brachyury gene in whole-mount TWis/TWis mutant embryos.

Development (Cambridge, England) - 1 Nov 1991

Herrmann B G

Abstract excerpt

The murine Brachyury (T) gene is required in mesoderm formation. Mutants carrying different T alleles show a graded severity of defects correlated with gene dosage along the body axis. The phenotypes range from shortening of the tail to the malformation of sacral vertebrae in heterozygotes, and to disruption of trunk development and embryonic death in homozygotes. Defects include a severe disturbance of the...

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PMID: 1821859
DOI: 10.1242/dev.113.3.913

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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