A PhoP-repressed gene promotes Salmonella typhimurium invasion of epithelial cells.

doi:10.1128/jb.175.14.4475-4484.1993

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Article

A PhoP-repressed gene promotes Salmonella typhimurium invasion of epithelial cells.

Journal of bacteriology - 1 Jul 1993

Behlau I, Miller S I

Abstract excerpt

The Salmonella typhimurium transcriptional regulators, PhoP/PhoQ, induce phoP-activated gene (pag) expression to promote virulence and intracellular survival within macrophages. This response to the macrophage intracellular environment is simulated by phoP/phoQ constitutive mutations (phenotype P...

Topics

Animals
Bacterial Adhesion
Bacterial Proteins
Cell Line
Cells, Cultured
Chromosome Mapping
DNA Transposable Elements
Epithelium
Gene Expression Regulation, Bacterial
Genes, Bacterial
Genetic Linkage
Genotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Macrophages

Mice

Mice, Inbred BALB C

Mutagenesis

Promoter Regions, Genetic

Salmonella typhimurium

Source

Open in PubMed Open full text

Identifiers

PMID: 8392513
DOI: 10.1128/jb.175.14.4475-4484.1993
PMCID: PMC204888

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8392513-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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