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Article

A PhoP-repressed gene promotes Salmonella typhimurium invasion of epithelial cells.

Journal of bacteriology - 1 Jul 1993

Behlau I, Miller S I

Abstract excerpt

The Salmonella typhimurium transcriptional regulators, PhoP/PhoQ, induce phoP-activated gene (pag) expression to promote virulence and intracellular survival within macrophages. This response to the macrophage intracellular environment is simulated by phoP/phoQ constitutive mutations (phenotype PhoPc) that increase the expression of pag genes and repress the synthesis of approximately 20 proteins encoded by...

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Identifiers

PMID: 8392513
DOI: 10.1128/jb.175.14.4475-4484.1993
PMCID: PMC204888

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