Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Hyper-invasive mutants define a novel Pho-regulated invasion pathway in Escherichia coli.

Molecular microbiology - 1 Dec 1993

Sinai A P, Bavoil P M

Abstract excerpt

We have isolated two transposon insertion mutations of the pst-phoU operon which result in the constitutive expression of the phoA gene product, alkaline phosphatase. The two mutations also render Escherichia coli invasive towards cultured HEp-2 cells and define a novel Pho-regulated invasion pathway. The presence of the large 'invasion' plasmid derived from an entero-invasive E. coli (EIEC) clinical isolate in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Base Sequence
Share to Cell Line
Share to Chromosome Mapping

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Escherichia coli

Share to Genes, Bacterial

Share to Molecular Sequence Data

Share to Mutation

Share to Plasmids

Source

Identifiers

PMID: 7934862
DOI: 10.1111/j.1365-2958.1993.tb00982.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Hyper-invasive mutants define a novel Pho-regulated invasion pathway in Escherichia coli.PMID 7934862Read ↗

Characterization of virulence genes of enteroinvasive Escherichia coli by TnphoA mutagenesis: identification of invX, a gene required for entry into HEp-2 cells.Semantic proximity Read ↗

A PhoP-repressed gene promotes Salmonella typhimurium invasion of epithelial cells.Semantic proximity Read ↗

Contribution of the <i>pst-phoU</i> Operon to Cell Adherence by Atypical Enteropathogenic <i>Escherichia coli</i> and Virulence of <i>Citrobacter rodentium</i>Semantic proximity Read ↗

Genome-wide transcriptional response of an avian pathogenic Escherichia coli (APEC) pst mutant.Semantic proximity Read ↗

PhoB Activates Escherichia coli O157:H7 Virulence Factors in Response to Inorganic Phosphate LimitationSemantic proximity Read ↗

Identification of a mutation in the pst-phoU operon that reduces pathogenicity of an Escherichia coli strain causing septicemia in pigs.Semantic proximity Read ↗

Environmental regulation of Salmonella typhi invasion-defective mutants.Semantic proximity Read ↗

Generalized transposon shuttle mutagenesis in Neisseria gonorrhoeae: a method for isolating epithelial cell invasion-defective mutants.Semantic proximity Read ↗

Molecular genetic analysis of the Escherichia coli phoP locus.Semantic proximity Read ↗

Construction and analysis of TnphoA mutants of enteropathogenic Escherichia coli unable to invade HEp-2 cells.Semantic proximity Read ↗

<i>Escherichia coli</i> O157:H7 responds to phosphate starvation by modifying LPS involved in biofilm formationSemantic proximity Read ↗

Activation of the cryptic PhnE permease promotes rapid adaptive evolution in a population of Escherichia coli K-12 starved for phosphate.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.