Article
Hyper-invasive mutants define a novel Pho-regulated invasion pathway in Escherichia coli.
Molecular microbiology - 1 Dec 1993
Sinai A P, Bavoil P M
Abstract excerpt
We have isolated two transposon insertion mutations of the pst-phoU operon which result in the constitutive expression of the phoA gene product, alkaline phosphatase. The two mutations also render Escherichia coli invasive towards cultured HEp-2 cells and define a novel Pho-regulated invasion pat...
Topics
- Alkaline Phosphatase
- Antigens, Bacterial
- Base Sequence
- Cell Line
- Chromosome Mapping
- DNA Transposable Elements
- DNA, Bacterial
- Escherichia coli
- Gene Expression Regulation, Bacterial
- Genes, Bacterial
- Humans
- Molecular Sequence Data