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Article

The PhoP virulence regulon and live oral Salmonella vaccines.

Vaccine - 1 Jan 1993

Miller S I, Loomis W P, Alpuche-Aranda C, Behlau I, Hohmann E

Abstract excerpt

The PhoP virulence regulon is essential to Salmonella typhimurium mouse typhoid fever pathogenesis and survival within macrophages. This virulence regulon is composed of the PhoP (transcriptional regulator) and PhoQ (environmental sensor) proteins and the genetic loci they positively (pags for PhoP activated genes) and negatively (prgs for PhoP repressed genes) regulate. Three regulated loci pagC, pagD, and prgH,...

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PMID: 8438611
DOI: 10.1016/0264-410x(93)90006-j

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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