Transcriptional autoregulation of the Salmonella typhimurium phoPQ operon.

doi:10.1128/jb.177.15.4364-4371.1995

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Article

Transcriptional autoregulation of the Salmonella typhimurium phoPQ operon.

Journal of bacteriology - 1 Aug 1995

Soncini F C, Véscovi E G, Groisman E A

Abstract excerpt

The Salmonella typhimurium PhoP-PhoQ two-component regulatory system controls the expression of several genes, some of which are necessary for virulence. During a screening for PhoP-regulated genes, we identified the phoPQ operon as a PhoP-activated locus. beta-Galactosidase activity originating from phoPQ-lac transcriptional fusions required the presence of both the transcriptional regulator PhoP and its cognate...

Topics

Bacterial Proteins
Base Sequence
Cloning, Molecular
DNA Transposable Elements
Gene Expression Regulation, Bacterial
Homeostasis
Lac Operon
Models, Genetic
Molecular Sequence Data
Mutation
Nucleic Acid Conformation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Operon

Promoter Regions, Genetic

RNA, Bacterial

RNA, Messenger

Salmonella typhimurium

Transcription Factors

Transcription, Genetic

Source

Open in PubMed Open full text

Identifiers

PMID: 7543474
DOI: 10.1128/jb.177.15.4364-4371.1995
PMCID: PMC177185

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7543474-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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