Article
Genome-wide transcriptional response of an avian pathogenic Escherichia coli (APEC) pst mutant.
BMC genomics - 28 Nov 2008
Crépin Sébastien, Lamarche Martin G, Garneau Philippe, Séguin Julie, Proulx Julie, Dozois Charles M, Harel Josée
Abstract excerpt
BACKGROUND: Avian pathogenic E. coli (APEC) are associated with extraintestinal diseases in poultry. The pstSCAB-phoU operon belongs to the Pho regulon and encodes the phosphate specific transport (Pst) system. A functional Pst system is required for full virulence in APEC and other bacteria and contributes to resistance of APEC to serum, to cationic antimicrobial peptides and acid shock. The global mechanisms...
Topics
- Animals
- Birds
- Escherichia coli
- Escherichia coli Proteins
- Fimbriae, Bacterial
- Gene Expression Profiling
- Gene Expression Regulation, Bacterial
- Genome, Bacterial
- Mutation
- Oligonucleotide Array Sequence Analysis