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Article

Salmonella typhimurium virulence genes are induced upon bacterial invasion into phagocytic and nonphagocytic cells.

Infection and immunity - 1 Nov 1999

Pfeifer C G, Marcus S L, Steele-Mortimer O, Knodler L A, Finlay B B

Abstract excerpt

Survival and growth of salmonellae within host cells are important aspects of bacterial virulence. We have developed an assay to identify Salmonella typhimurium genes that are induced inside Salmonella-containing vacuoles within macrophage and epithelial cells. A promoterless luciferase gene cassette was inserted randomly into the Salmonella chromosome, and the resulting mutants were screened for genes...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 10531217
DOI: 10.1128/IAI.67.11.5690-5698.1999
PMCID: PMC96943

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