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Article

Constitutively expressed phoP inhibits mouse-virulence of Salmonella typhimurium in an Spv-dependent manner.

Microbiology and immunology - 1 Jan 2000

Matsui H, Kawakami T, Ishikawa S, Danbara H, Gulig P A

Abstract excerpt

In Salmonella typhimurium, the transcription of several virulence genes including spvB is regulated by the PhoP/PhoQ regulatory system. To further examine the relationship between the PhoP/PhoQ and Spv systems for virulence in mice, we examined a non-polar phoP mutation combined with different virulence plasmid genotypes for effects on virulence of S. typhimurium in the mouse model. PhoP-/Spv+ and PhoP-/Spv-...

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PMID: 10941927
DOI: 10.1111/j.1348-0421.2000.tb02519.x

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