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Article

p53 mutations in cervical carcinogenesis--low frequency and lack of correlation with human papillomavirus status.

British journal of cancer - 1 Apr 1994

Busby-Earle R M, Steel C M, Williams A R, Cohen B, Bird C C

Abstract excerpt

p53 gene aberrations are common in human malignancies, and recent studies suggest that in cervical carcinoma p53 function is inactivated either by complex formation with human papillomavirus (HPV) E6 product or by gene mutation. Using polymerase chain reaction (PCR) followed by denaturing gradient gel electrophoresis (DGGE), we examined the mutational status of the four 'hotspot' regions of the p53 gene in 47...

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Share to Electrophoresis, Polyacrylamide Gel

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Genes, p53

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Source

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Identifiers

PMID: 8142262
DOI: 10.1038/bjc.1994.138
PMCID: PMC1968818

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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