Article
Analysis of the p53 gene and papillomavirus detection in smears from cervical lesions.
Sao Paulo medical journal = Revista paulista de medicina - 3 Jan 2002
dos Santos Oliveira Ledy do Horto, Fernandez André de Paula, Xavier Brunno Lessa Saldanha, Machado Rodrigues Eliana de Vasconcelos, Cavalcanti Silvia Maria Baeta
Abstract excerpt
CONTEXT: Alterations of the p53 tumor suppressor gene are correlated with a critical step in the development of many human cancers. The tumor suppressor gene functions include regulation of the cell cycle and the cellular response to DNA damage, initiation of DNA repair and replication, induction of apoptosis and promotion of cell differentiation. CASE REPORT: Smears from ten cases of cervical lesions were...
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