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Article

Abnormalities in the p53 gene in tumors and cell lines of human squamous-cell carcinomas of the head and neck.

International journal of cancer - 8 May 1993

Yin X Y, Smith M L, Whiteside T L, Johnson J T, Herberman R B, Locker J

Abstract excerpt

Abnormalities in the p53 gene were studied in a series of cell lines of human squamous-cell carcinoma of the head and neck (SCCHN) and in tumor tissues. Restriction-fragment-length polymorphism (RFLP), quantitative hybridization and immunochemical analysis of mutant p53 proteins were combined to detect and characterize 3 different phases in the p53 gene alteration: mutation (in 9/9 cases), 17p13 deletion (9/10...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 8098018
DOI: 10.1002/ijc.2910540226

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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