Article
TP53 polymorphism at exon 4 in caucasian women from eastern France: lack of correlation with HPV status and grade of cervical precancerous lesions.
European journal of obstetrics, gynecology, and reproductive biology - 10 Jun 2002
Humbey Olivier, Aubin François, Cairey-Remonnay Sandrine, Riethmuller Didier, Pretet Jean Luc, Fest Thierry, Seilles Estelle, Mougin Christiane
Abstract excerpt
OBJECTIVE: To investigate the codon 72 TP53 polymorphism in women from eastern France with normal or abnormal cervical cytology. STUDY DESIGN: We analyzed the TP53 allele distribution by denaturant gradient gel electrophoresis assay and the human papillomaviruses (HPV) infection in 138 cervical smears: 50 normal, 20 atypical squamous cells of undetermined significance, 40 low grade squamous intraepithelial...
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