Article
The status of the p53 gene in human papilloma virus positive or negative cervical carcinoma cell lines.
Carcinogenesis - 1 Jul 1992
Srivastava S, Tong Y A, Devadas K, Zou Z Q, Chen Y, Pirollo K F, Chang E H
Abstract excerpt
We have analyzed p53 gene alterations in five cervical cancer derived cell lines. Two of the five cervical cancer cell lines, HTB31 (C-33A) and 32 (HT-3), harbored missense mutations in codons 273 and 245 respectively, whereas the other three tumor cell lines, HTB33 (ME180), 34 (MS751) and 35 (SIHA), did not reveal any mutation in the p53 coding sequence spanning codons 126-307. Although all the tumor cell lines...
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