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Article

The status of the p53 gene in human papilloma virus positive or negative cervical carcinoma cell lines.

Carcinogenesis - 1 Jul 1992

Srivastava S, Tong Y A, Devadas K, Zou Z Q, Chen Y, Pirollo K F, Chang E H

Abstract excerpt

We have analyzed p53 gene alterations in five cervical cancer derived cell lines. Two of the five cervical cancer cell lines, HTB31 (C-33A) and 32 (HT-3), harbored missense mutations in codons 273 and 245 respectively, whereas the other three tumor cell lines, HTB33 (ME180), 34 (MS751) and 35 (SIHA), did not reveal any mutation in the p53 coding sequence spanning codons 126-307. Although all the tumor cell lines...

Topics

Amino Acid Sequence
Base Sequence
Codon
Female
Genes, p53
Humans
Mutation
Papillomaviridae
Tumor Suppressor Protein p53
Uterine Cervical Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 1322252
DOI: 10.1093/carcin/13.7.1273

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1322252-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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