[Analysis of p53 gene in gynecologic tumors].

Article

[Analysis of p53 gene in gynecologic tumors].

Rinsho byori. The Japanese journal of clinical pathology - 1 Mar 1994

Yaginuma Y, Yamashita T, Duenas J C, Katayama H, Ishikawa M

Abstract excerpt

The inactivation of the tumor suppressor gene p53 has been demonstrated in a variety of human tumors. Herein, we performed a p53 gene analysis of human gynecologic tumor cell lines and tumor tissues. In the SK-OV-3 cell line, Southern analysis suggested the presence of sequence deletions/rearrang...

Topics

Base Sequence
Female
Gene Expression Regulation, Neoplastic
Genes, Tumor Suppressor
Genes, p53
Genital Neoplasms, Female
Humans
Molecular Sequence Data
Mutation
Polymerase Chain Reaction

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