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Article

Genetic alterations of the TP53 gene, p53 protein expression and HPV infection in primary cervical carcinomas.

The Journal of pathology - 1 Oct 1993

Helland A, Holm R, Kristensen G, Kaern J, Karlsen F, Trope C, Nesland J M, Børresen A L

Abstract excerpt

Primary cervical carcinomas from 92 patients were investigated for genetic alterations in the tumour suppressor gene TP53. Studies of allelic imbalance (AI) were performed by Southern blot analysis and by using two PCR (polymerase chain reaction) polymorphisms within the TP53 gene. AI in the tumour was observed in 22 per cent (11 of 52 informative patients) and was significantly associated with recurrence both in...

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Identifiers

PMID: 8283348
DOI: 10.1002/path.1711710207

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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