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Article

Genetic mapping of the BRCA1 region on chromosome 17q21.

American journal of human genetics - 1 Mar 1994

Albertsen H, Plaetke R, Ballard L, Fujimoto E, Connolly J, Lawrence E, Rodriguez P, Robertson M, Bradley P, Milner B

Abstract excerpt

Chromosome 17q21 harbors a gene (BRCA1) associated with a hereditary form of breast cancer. As a step toward identification of this gene itself we developed a number of simple-sequence-repeat (SSR) markers for chromosome 17 and constructed a high-resolution genetic map of a 40-cM region around 17q21. As part of this effort we captured genotypes from five of the markers by using an ABI sequencing instrument and...

Topics

Base Sequence
Breast Neoplasms
Chromosome Mapping
Chromosomes, Artificial, Yeast
Chromosomes, Human, Pair 17
DNA Primers
Female
Genetic Linkage
Genetic Markers
Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genotype

Humans

Molecular Sequence Data

Polymerase Chain Reaction

Repetitive Sequences, Nucleic Acid

Source

Open in PubMed Open full text

Identifiers

PMID: 8116621
PMCID: PMC1918118

Genes

BRCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8116621-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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