Genetic counseling for families with inherited susceptibility to breast and ovarian cancer.

Article

Genetic counseling for families with inherited susceptibility to breast and ovarian cancer.

JAMA - 21 Apr 1993

Biesecker B B, Boehnke M, Calzone K, Markel D S, Garber J E, Collins F S, Weber B L

Abstract excerpt

Efforts are under way to isolate a gene (BRCA1) on chromosome 17q12-21. Mutations in this gene predispose women to breast and ovarian cancer. Women with germline mutations in BRCA1 are estimated to have an 85% lifetime risk of developing breast cancer and an increased but as yet undetermined risk...

Topics

Breast Neoplasms
Chromosome Mapping
Chromosomes, Human, Pair 17
Female
Genetic Carrier Screening
Genetic Counseling
Genetic Testing
Humans
Mutation
Ovarian Neoplasms
Pedigree
Social Support

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