Article
A radiation hybrid map of the BRCA1 region.
American journal of human genetics - 1 Mar 1994
O'Connell P, Albertsen H, Matsunami N, Taylor T, Hundley J E, Johnson-Pais T L, Reus B, Lawrence E, Ballard L, White R
Abstract excerpt
A locus on chromosome 17q, designated "BRCA1," has been identified as a predisposition gene for breast cancer. A panel of chromosome 17-specific radiation-reduced somatic cell hybrid clones has been assembled for high-resolution mapping of chromosome 17. A series of 35 markers, known to span the BRCA1 locus, were tested against this hybrid panel by PCR assays. Statistical analysis of these data yields a BRCA1...
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