Evidence for involvement of BRCA1 in sporadic breast carcinomas.

Article

Evidence for involvement of BRCA1 in sporadic breast carcinomas.

Cancer research - 15 May 1994

Cropp C S, Nevanlinna H A, Pyrhönen S, Stenman U H, Salmikangas P, Albertsen H, White R, Callahan R

Abstract excerpt

The hereditary breast cancer gene BRCA1 previously has been localized to chromosome 17q21. We looked for evidence of involvement of this region of chromosome 17 in 130 sporadic breast cancers. Seventeen polymorphic sequence tagged site markers were examined in these tumors between the D17S250 and...

Topics

Breast Neoplasms
Chromosome Mapping
Chromosomes, Human, Pair 17
Female
Gene Deletion
Genotype
Humans
Polymorphism, Genetic

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