High-density genetic map of the BRCA1 region of chromosome 17q12-q21.

doi:10.1006/geno.1993.1381

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

High-density genetic map of the BRCA1 region of chromosome 17q12-q21.

Genomics - 1 Sept 1993

Anderson L A, Friedman L, Osborne-Lawrence S, Lynch E, Weissenbach J, Bowcock A, King M C

Abstract excerpt

To facilitate the positional cloning of the breast-ovarian cancer gene BRCA1, we constructed a high-density genetic map of the 8.3-cM interval between D17S250 and GIP on chromosome 17q12-q21. Markers were mapped by linkage in the CEPH and in extended kindreds in our breast cancer series. The map...

Topics

Alleles
Base Sequence
Breast Neoplasms
Chromosome Mapping
Chromosomes, Human, Pair 17
DNA
DNA Primers
Female
Gastric Inhibitory Polypeptide
Gene Frequency
Genetic Markers
Genotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Hybrid Cells

Molecular Sequence Data

Oncogenes

Ovarian Neoplasms

Polymorphism, Genetic

Source

Open in PubMed

Identifiers

PMID: 8244378
DOI: 10.1006/geno.1993.1381

Genes

BRCA1
GIP
KRT10
PPY
RARA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8244378-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

High-density genetic map of the BRCA1 region of chromosome 17q12-q21.PMID 8244378Read ↗

Genetic mapping of the BRCA1 region on chromosome 17q21.Semantic proximity Read ↗

Localisation of the breast-ovarian cancer susceptibility gene (BRCA1) on 17q12-21 to an interval of < or = 1 cM.Semantic proximity Read ↗

Characterization of 10 new polymorphic dinucleotide repeats and generation of a high-density microsatellite-based physical map of the BRCA1 region of chromosome 17q21.Semantic proximity Read ↗

A breast-ovarian cancer susceptibility gene maps to chromosome 17q21.Semantic proximity Read ↗

A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1.Semantic proximity Read ↗

A radiation hybrid map of the BRCA1 region.Semantic proximity Read ↗

A genetic map of human chromosome 17p.Semantic proximity Read ↗

Physical mapping, cloning, and identification of genes within a 500-kb region containing BRCA1.Semantic proximity Read ↗

22 genes from chromosome 17q21: cloning, sequencing, and characterization of mutations in breast cancer families and tumors.Semantic proximity Read ↗

CGH analysis of familial non-BRCA1/BRCA2 breast tumors and mutation screening of a candidate locus on chromosome 17q11.2-12.Semantic proximity Read ↗

THRA1 and D17S183 flank an interval of < 4 cM for the breast-ovarian cancer gene (BRCA1) on chromosome 17q21.Semantic proximity Read ↗

A large kindred with 17q-linked breast and ovarian cancer: genetic, phenotypic, and genealogical analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.