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Article

Detailed deletion analysis of sporadic breast tumors defines an interstitial region of allelic loss on 17q25.

Genes, chromosomes & cancer - 1 Sept 1996

Kalikin L M, Qu X, Frank T S, Caduff R F, Svoboda S M, Law D J, Petty E M

Abstract excerpt

Whole genome analyses of breast tumors with polymorphic markers have detected nonrandom loss of heterozygosity on multiple chromosomes, providing clues to the locations of suspected tumor suppressor genes. Tumors are thought to initiate, progress, and metastasize as mutations accumulate in multiple growth-regulatory genes; thus, identification and characterization of these genes are critical to understanding and...

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PMID: 8889509
DOI: 10.1002/(SICI)1098-2264(199609)17:1<64::AID-GCC10>3.0.CO;2-H

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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