A breast-ovarian cancer susceptibility gene maps to chromosome 17q21.

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Article

A breast-ovarian cancer susceptibility gene maps to chromosome 17q21.

American journal of human genetics - 1 Apr 1993

Feunteun J, Narod S A, Lynch H T, Watson P, Conway T, Lynch J, Parboosingh J, O'Connell P, White R, Lenoir G M

Abstract excerpt

Nineteen North American Caucasian families that contain a minimum of four confirmed cases of breast or ovarian cancer have been studied. Four polymorphisms (cLB17.1, D17S579, D17S588, and D17S74), which span a region of approximately 15 cM on chromosome 17q12, were typed. Our data confirm the loc...

Topics

Adult
Aged
Breast Neoplasms
Canada
Chromosome Mapping
Chromosomes, Human, Pair 17
Family Health
Female
Gene Expression
Genes, Dominant
Genetic Linkage
Genetic Markers
Genetic Predisposition to Disease
Genotype
Humans
Lod Score
Male
Middle Aged

Source

Open in PubMed Open full text

Identifiers

PMID: 8460639
PMCID: PMC1682073

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8460639-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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