Article
Characterization of 10 new polymorphic dinucleotide repeats and generation of a high-density microsatellite-based physical map of the BRCA1 region of chromosome 17q21.
Genomics - 1 Dec 1994
Couch F J, Kiousis S, Castilla L H, Xu J, Chandrasekharappa S C, Chamberlain J S, Collins F S, Weber B L
Abstract excerpt
A familial early onset breast cancer gene (BRCA1) has been localized to chromosome 17q21. To aid in the identification of this gene a number of new microsatellite markers from the D17S857 to D17S78 region were isolated and characterized. These markers, along with previously published markers from...
Topics
- Alleles
- Base Sequence
- Breast Neoplasms
- Chromosome Mapping
- Chromosomes, Human, Pair 17
- Cosmids
- DNA Primers
- DNA, Neoplasm
- DNA, Satellite
- Female
- Gene Frequency
- Genetic Markers
- Humans
- Molecular Sequence Data
- Oligodeoxyribonucleotides