Article
Allele loss on chromosome 17 in ovarian cystic teratomas.
Japanese journal of clinical oncology - 1 Aug 1994
Kido M, Ito K, Shibuya M
Abstract excerpt
We examined the DNA from 12 patients with ovarian tumors (four benign germ cell tumors, one malignant germ cell tumor, one benign common epithelial tumor and six common epithelial carcinomas) for the allele loss on chromosome 17 using 12 probes for hypervariable loci. At THH59 loss of heterozygosity (LOH) was detected in three benign germ cell tumors and two epithelial carcinomas. At a more distal locus, KKA35,...
Topics
- Alleles
- Blotting, Southern
- Chromosome Deletion
- Chromosomes, Human, Pair 17
- Female
- Germinoma
- Heterozygote
- Humans
- Ovarian Neoplasms
- Teratoma