Article
Allele losses on chromosome 17 in human epithelial ovarian carcinoma.
Oncogene - 1 Oct 1990
Eccles D M, Cranston G, Steel C M, Nakamura Y, Leonard R C
Abstract excerpt
16 epithelial ovarian carcinomas (12 serous, 2 mucinous and 2 endometrioid) and 2 benign ovarian adenomas were studied using recombinant DNA technology to compare loci on chromosome 17 in germ-line and tumour DNA. Four polymorphic probes mapping to 17p and one mapping to 17q were used. There was a high frequency of allele loss on 17q/(77%) and a slightly lower frequency on 17p (69%). These findings probably...
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