Article
Loss of heterozygosity of chromosome 17 in human borderline and invasive epithelial ovarian tumors.
Oncogene - 16 May 1996
Wertheim I, Tangir J, Muto M G, Welch W R, Berkowitz R S, Chen W Y, Mok S C
Abstract excerpt
Polymerase chain reaction (PCR) analysis of microsatellite polymorphisms corresponding to four loci which map to chromosome 17p and 11 loci which map to chromosome 17q was performed to screen for loss of heterozygosity (LOH) in paired normal and tumor tissues from 27 cases of borderline epithelial ovarian tumors (BEOT) and 32 cases of invasive epithelial ovarian cancers (IOC). LOH was observed in six of 27 (22%)...
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