Article
Allele loss from chromosome 17 in ovarian cancer.
Oncogene - 1 Oct 1990
Russell S E, Hickey G I, Lowry W S, White P, Atkinson R J
Abstract excerpt
In a number of human cancers genes capable of suppressing tumorigenicity have been identified and in some instances cloned. Successful isolation of such tumour suppressor genes has depended upon either the mapping of a locus which confers susceptibility to a specific tumour, or the finding of specific allele loss in the tumour cells of heterozygous individuals. In ovarian cancer it is known that a small...
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