Activator-induced conformational change in general transcription factor TFIIB.

doi:10.1038/371717a0

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Article

Activator-induced conformational change in general transcription factor TFIIB.

Nature - 20 Oct 1994

Roberts S G, Green M R

Abstract excerpt

Transcriptional activator proteins (activators) function, at least in part, by increasing preinitiation complex assembly (for reviews see refs 1-4). Previous studies have shown that an acidic activator forms a contact with the general transcription factor TFIIB (refs 5-7) and recruits it into the...

Topics

Glutathione Transferase
Herpes Simplex Virus Protein Vmw65
Mutation
Protein Binding
Protein Conformation
Recombinant Fusion Proteins
Transcription Factor TFIIB
Transcription Factors

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