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Article

Structural insight into the TFIIE-TFIIH interaction: TFIIE and p53 share the binding region on TFIIH.

The EMBO journal - 9 Apr 2008

Okuda Masahiko, Tanaka Aki, Satoh Manami, Mizuta Shoko, Takazawa Manabu, Ohkuma Yoshiaki, Nishimura Yoshifumi

Abstract excerpt

RNA polymerase II and general transcription factors (GTFs) assemble on a promoter to form a transcription preinitiation complex (PIC). Among the GTFs, TFIIE recruits TFIIH to complete the PIC formation and regulates enzymatic activities of TFIIH. However, the mode of binding between TFIIE and TFI...

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Share to Phosphorylation
Share to Protein Structure, Secondary
Share to Protein Subunits

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Trans-Activators

Share to Transcription Factor TFIID

Share to Transcription Factor TFIIH

Share to Transcription Factors, TFII

Share to Tumor Suppressor Protein p53

Source

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Identifiers

PMID: 18354501
DOI: 10.1038/emboj.2008.47
PMCID: PMC2275666

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18354501-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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