Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Interaction between an acidic activator and transcription factor TFIIB is required for transcriptional activation.

Nature - 24 Jun 1993

Roberts S G, Ha I, Maldonado E, Reinberg D, Green M R

Abstract excerpt

How eukaryotic promoter-specific activator proteins (activators) stimulate transcription is a central question. We have previously shown that an acidic activator can directly interact with the general transcription factor TFIIB and increase its stable assembly into a preinitiation complex. We have proposed that this increase in TFIIB assembly is at least part of the mechanism by which an acidic activator...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Binding Sites
Share to Cloning, Molecular
Share to Fungal Proteins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mutation

Share to Protein Binding

Share to Recombinant Fusion Proteins

Share to Transcription Factors

Share to Transcription, Genetic

Source

Identifiers

PMID: 8515819
DOI: 10.1038/363741a0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Interaction between an acidic activator and transcription factor TFIIB is required for transcriptional activation.PMID 8515819Read ↗

Activator-induced conformational change in general transcription factor TFIIB.Semantic proximity Read ↗

A role for activator-mediated TFIIB recruitment in diverse aspects of transcriptional regulation.Semantic proximity Read ↗

Transcriptional activation by TFIIB mutants that are severely impaired in interaction with promoter DNA and acidic activation domains.Semantic proximity Read ↗

Design principles of acidic transcriptional activation domainsSemantic proximity Read ↗

Activator-mediated disruption of sequence-specific DNA contacts by the general transcription factor TFIIB.Semantic proximity Read ↗

The TBP-TFIIA interaction in the response to acidic activators in vivo.Semantic proximity Read ↗

Transcription factor IIB acetylates itself to regulate transcription.Semantic proximity Read ↗

The strength of acidic activation domains correlates with their affinity for both transcriptional and non-transcriptional proteins.Semantic proximity Read ↗

New eukaryotic transcriptional repressors.Semantic proximity Read ↗

Intramolecular interaction of yeast TFIIB in transcription control.Semantic proximity Read ↗

xUBF contains a novel dimerization domain essential for RNA polymerase I transcription.Semantic proximity Read ↗

Analysis of the role of TFIIE in transcriptional regulation through structure-function studies of the TFIIEbeta subunit.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.