Article
xUBF contains a novel dimerization domain essential for RNA polymerase I transcription.
Genes & development - 1 Nov 1991
McStay B, Frazier M W, Reeder R H
Abstract excerpt
Xenopus laevis upstream binding factor (xUBF) is an RNA polymerase I transcription factor that is required for formation of the stable initiation complex. The 701-amino-acid protein contains three regions of homology to the chromosomal protein HMG1 (the HMG boxes), which act in comparative independence to cause DNA binding. DNA binding is augmented by a 102-residue amino-terminal domain that causes xUBF to form...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Binding Sites
- DNA, Ribosomal
- DNA-Binding Proteins
- Glutaral
- Macromolecular Substances
- Molecular Sequence Data
- Mutation
- Nucleoproteins