Article
Altered intracellular targeting properties associated with mutations in the Legionella pneumophila dotA gene.
Molecular microbiology - 1 Nov 1994
Berger K H, Merriam J J, Isberg R R
Abstract excerpt
Legionella pneumophila dot mutations cause defects in intracellular targeting of the microorganism within cultured macrophages. Each of the previously characterized dot mutations was shown to be complemented by a single open reading frame designated dotA. The defects caused by the mutations appear to be due to disrupted function of the predicted 1048-amino-acid residue DotA protein, and not by polarity effects on...
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