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Article

Molecular and structural analysis of Legionella DotI gives insights into an inner membrane complex essential for type IV secretion.

Scientific reports - 3 Jun 2015

Kuroda Takuya, Kubori Tomoko, Thanh Bui Xuan, Hyakutake Akihiro, Uchida Yumiko, Imada Katsumi, Nagai Hiroki

Abstract excerpt

The human pathogen Legionella pneumophila delivers a large array of the effector proteins into host cells using the Dot/Icm type IVB secretion system. Among the proteins composing the Dot/Icm system, an inner membrane protein DotI is known to be crucial for the secretion function but its structure and role in type IV secretion had not been elucidated. We report here the crystal structures of the periplasmic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26039110
DOI: 10.1038/srep10912
PMCID: PMC4454188

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Molecular and structural analysis of Legionella DotI gives insights into an inner membrane complex essential for type IV secretion.PMID 26039110Read ↗

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