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Article

Identification of linked Legionella pneumophila genes essential for intracellular growth and evasion of the endocytic pathway.

Infection and immunity - 1 Mar 1998

Andrews H L, Vogel J P, Isberg R R

Abstract excerpt

Legionella pneumophila replicates within a specialized phagosome in cultured cells, a function necessary for its pathogenicity. The replicative phagosome lacks membrane marker proteins, such as the glycoprotein LAMP-1, that are indicators of the normal endocytic pathway. We describe the isolation of several Legionella genes essential for intracellular growth and evasion of the endocytic pathway, using a genetic...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 9488381
DOI: 10.1128/IAI.66.3.950-958.1998
PMCID: PMC108001

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Source receipt: pubmed, retrieved 7 Sept 2026.

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