Analysis of direct and inverted DJH rearrangements in a human Ig heavy chain transgenic minilocus.

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Article

Analysis of direct and inverted DJH rearrangements in a human Ig heavy chain transgenic minilocus.

Journal of immunology (Baltimore, Md. : 1950) - 15 Jun 1995

Tuaillon N, Miller A B, Tucker P W, Capra J D

Abstract excerpt

D to JH rearrangement can occur either by a deletional or an inversional mechanism. In this study, we have analyzed deletional and inversional D to JH recombination in a human Ig heavy chain transgenic minilocus. The analysis of these events in a transgenic minilocus rather than in vivo in the hu...

Topics

Animals
Base Sequence
Cloning, Molecular
DNA
Gene Deletion
Gene Rearrangement, B-Lymphocyte, Heavy Chain
Humans
Immunoglobulin Heavy Chains
Mice
Mice, Transgenic
Molecular Sequence Data
Mutation
Reading Frames
Recombination, Genetic
Sequence Homology, Nucleic Acid

Source

Open in PubMed

Identifiers

PMID: 7759881

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7759881-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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