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Article

Somatic hypermutation of immunoglobulin ĸ light chain genes

1996-01-01

Abstract excerpt

Somatic hypermutation of immunoglobulin genes is a tightly controlled, site directed process. The nucleotide changes are targeted in the region surrounding the rearranged V gene segment of the heavy and light chain loci. The targeting of somatic mutation does neither require V region including the Vĸ promoter specific features nor a specific distance between the C ĸ and the 3' enhancer. On the other hand, removal...

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Literature Corpus work
c419b436-467f-5251-82c1-e35f19240aad
DOI
10.21954/ou.ro.0000f7ad
Open publication

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Somatic hypermutation of immunoglobulin ĸ light chain genesDOI 10.21954/ou.ro.0000f7ad
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