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Article

Transposon insertions causing constitutive Sex-lethal activity in Drosophila melanogaster affect Sxl sex-specific transcript splicing.

Genetics - 1 Feb 1995

Bernstein M, Lersch R A, Subrahmanyan L, Cline T W

Abstract excerpt

Sex-lethal (Sxl) gene products induce female development in Drosophila melanogaster and suppress the transcriptional hyperactivation of X-linked genes responsible for male X-chromosome dosage compensation. Control of Sxl functioning by the dose of X-chromosomes normally ensures that the female-specific functions of this developmental switch gene are only expressed in diplo-X individuals. Although the immediate...

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Identifiers

PMID: 7713421
DOI: 10.1093/genetics/139.2.631
PMCID: PMC1206370

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Transposon insertions causing constitutive Sex-lethal activity in Drosophila melanogaster affect Sxl sex-specific transcript splicing.PMID 7713421Read ↗

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