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Article

Imprinting of the Y chromosome influences dosage compensation in roX1 roX2 Drosophila melanogaster.

Genetics - 1 Nov 2009

Menon Debashish U, Meller Victoria H

Abstract excerpt

Drosophila melanogaster males have a well-characterized regulatory system that increases X-linked gene expression. This essential process restores the balance between X-linked and autosomal gene products in males. A complex composed of the male-specific lethal (MSL) proteins and RNA is recruited to the body of transcribed X-linked genes where it modifies chromatin to increase expression. The RNA components of...

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Identifiers

PMID: 19704014
DOI: 10.1534/genetics.109.107219
PMCID: PMC2778978

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Imprinting of the Y chromosome influences dosage compensation in roX1 roX2 Drosophila melanogaster.PMID 19704014Read ↗

The severity of roX1 mutations is predicted by MSL localization on the X chromosome.Semantic proximity Read ↗

Molecularly severe roX1 mutations contribute to dosage compensation in Drosophila.Semantic proximity Read ↗

roX1 RNA paints the X chromosome of male Drosophila and is regulated by the dosage compensation system.Semantic proximity Read ↗

Modulation of Heterochromatin by Male Specific Lethal Proteins and roX RNA in Drosophila melanogaster Males.Semantic proximity Read ↗

A mutually exclusive stem-loop arrangement in roX2 RNA is essential for X-chromosome regulation in Drosophila.Semantic proximity Read ↗

Tandem stem-loops in roX RNAs act together to mediate X chromosome dosage compensation in Drosophila.Semantic proximity Read ↗

Single-cell RNA-sequencing reveals pre-meiotic X-chromosome dosage compensation in <i>Drosophila testis</i>Semantic proximity Read ↗

The MRG domain mediates the functional integration of MSL3 into the dosage compensation complex.Semantic proximity Read ↗

Extent of chromatin spreading determined by roX RNA recruitment of MSL proteins.Semantic proximity Read ↗

Transposon insertions causing constitutive Sex-lethal activity in Drosophila melanogaster affect Sxl sex-specific transcript splicing.Semantic proximity Read ↗

Local spreading of MSL complexes from roX genes on the Drosophila X chromosome.Semantic proximity Read ↗

Generation of a useful roX1 allele by targeted gene conversion.Semantic proximity Read ↗

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