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Article

The severity of roX1 mutations is predicted by MSL localization on the X chromosome.

Mechanisms of development - 1 Oct 2005

Deng Xinxian, Rattner Barbara P, Souter Skye, Meller Victoria H

Abstract excerpt

Dosage compensation equalizes the expression of sex-linked genes between males and females. Most genes on the X chromosome of male Drosophila are transcribed at an increased level, contributing to compensation. The roX1 and roX2 genes produce non-coding transcripts that localize along the X-chromosome of male flies. Although lacking sequence similarity, they are necessary but redundant components of a system that...

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Source

Identifiers

PMID: 16125915
DOI: 10.1016/j.mod.2005.06.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The severity of roX1 mutations is predicted by MSL localization on the X chromosome.PMID 16125915Read ↗

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Tandem stem-loops in roX RNAs act together to mediate X chromosome dosage compensation in Drosophila.Semantic proximity Read ↗

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roX1 RNA paints the X chromosome of male Drosophila and is regulated by the dosage compensation system.Semantic proximity Read ↗

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