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Article

Differential effects of Sex-lethal mutations on dosage compensation early in Drosophila development.

Genetics - 1 Mar 1994

Bernstein M, Cline T W

Abstract excerpt

In response to the primary sex determination signal, X chromosome dose, the Sex-lethal gene controls all aspects of somatic sex determination and differentiation, including X chromosome dosage compensation. Two complementary classes of mutations have been identified that differentially affect Sxl somatic functions: (1) those impairing the "early" function used to set developmental pathway choice in response to...

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Identifiers

PMID: 8005414
DOI: 10.1093/genetics/136.3.1051
PMCID: PMC1205862

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Differential effects of Sex-lethal mutations on dosage compensation early in Drosophila development.PMID 8005414Read ↗

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