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Article

An interactive network of long non-coding RNAs facilitates the Drosophila sex determination decision.

Biochimica et biophysica acta - 1 Sept 2014

Mulvey Brett B, Olcese Ursula, Cabrera Janel R, Horabin Jamila I

Abstract excerpt

Genome analysis in several eukaryotes shows a surprising number of transcripts which do not encode conventional messenger RNAs. Once considered noise, these non-coding RNAs (ncRNAs) appear capable of controlling gene expression by various means. We find that Drosophila sex determination, specifically the master-switch gene Sex-lethal (Sxl), is regulated by long ncRNAs (>200nt). The lncRNAs influence the dose...

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Identifiers

PMID: 24954180
DOI: 10.1016/j.bbagrm.2014.06.007
PMCID: PMC4134978

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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