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Aphidicolin-resistant Chinese hamster ovary cells possess altered DNA polymerases of the alpha-family.

Biochimica et biophysica acta - 17 May 1994

Fehér Z, Mishra N C

Abstract excerpt

DNA polymerases alpha, delta and epsilon were partially purified and characterized from a wild type Chinese hamster ovary (CHO) cell line and from two aphidicolin-resistant mutant CHO cell lines (BR5 and BR5-20a). The main characteristics of the wild type and mutant DNA polymerases were compared in order to reveal differences in the properties of these enzymes responsible for the aphidicolin resistance of the...

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PMID: 7514891
DOI: 10.1016/0167-4781(94)90098-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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