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Article

Aphidicolin-resistant Chinese hamster ovary cells possess altered DNA polymerases of the alpha-family.

Biochimica et biophysica acta - 17 May 1994

Fehér Z, Mishra N C

Abstract excerpt

DNA polymerases alpha, delta and epsilon were partially purified and characterized from a wild type Chinese hamster ovary (CHO) cell line and from two aphidicolin-resistant mutant CHO cell lines (BR5 and BR5-20a). The main characteristics of the wild type and mutant DNA polymerases were compared...

Topics

Animals
Aphidicolin
Arabinofuranosylcytosine Triphosphate
CHO Cells
Chromatography, Ion Exchange
Cricetinae
Cricetulus
DNA
DNA Polymerase II
DNA-Directed DNA Polymerase
Drug Resistance
Electrophoresis, Polyacrylamide Gel

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Templates, Genetic

Vidarabine Phosphate

Source

Identifiers

PMID: 7514891
DOI: 10.1016/0167-4781(94)90098-1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7514891-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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