Article
Aphidicolin-resistant DNA polymerase of bacteriophage phi 29 APHr71 mutant is hypersensitive to phosphonoacetic acid and butylphenyldeoxyguanosine 5'-triphosphate.
Virology - 1 Sept 1990
Matsumoto K, Kim C I, Kobayashi H, Kanehiro H, Hirokawa H
Abstract excerpt
Bacteriophage phi 29 DNA polymerase is sensitive to aphidicolin (APH). DNA polymerase of the APH-resistant mutant, APHr71, was more sensitive to phosphonoacetic acid and butylphenyldeoxyguanosine 5'triphosphate than the wild type. Nucleotide sequence analysis revealed a single transition of G at...
Topics
- Amino Acid Sequence
- Antiviral Agents
- Aphidicolin
- Bacteriophages
- DNA Polymerase II
- Deoxyguanine Nucleotides
- Diterpenes
- Drug Resistance
- Microbial Sensitivity Tests
- Molecular Sequence Data
- Mutation