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Article

Isolation of Chinese hamster ovary cells with reduced poly(ADP-ribose) polymerase activity.

Mutation research - 1 Aug 1990

MacLaren R A, Witmer M V, Richardson E, Stamato T D

Abstract excerpt

The biological function of poly(ADP-ribose) polymerase in DNA repair, cell-cycle regulation and cellular differentiation has yet to be defined. Isolation of cells which are deficient in poly(ADP-ribose) synthesis would greatly facilitate the determination of the biological role of this enzyme. A method is described for isolating Chinese hamster ovary (CHO) cells deficient in the poly(ADP-ribose) polymerase...

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Identifiers

PMID: 2117253
DOI: 10.1016/0027-5107(90)90032-y

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Isolation of Chinese hamster ovary cells with reduced poly(ADP-ribose) polymerase activity.PMID 2117253Read ↗

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