Article
High-resolution mapping of the human T-cell leukemia virus type 1 Rex-binding element by in vitro selection.
Journal of virology - 1 Dec 1995
Baskerville S, Zapp M, Ellington A D
Abstract excerpt
Interactions between the Rex protein of HTLV-1 and the genomic Rex-binding element (XBE) mediate the cytoplasmic transport of viral mRNAs. However, it is uncertain which RNA sequences and structures contribute to Rex recognition. A portion of the viral genome that spanned the XBE was partially ra...
Topics
- Base Composition
- Base Sequence
- Binding Sites
- Cloning, Molecular
- Conserved Sequence
- Gene Products, rex
- Genetic Variation
- Human T-lymphotropic virus 1
- Humans
- Molecular Sequence Data
- Mutagenesis, Site-Directed
- Nucleic Acid Conformation
- Oligodeoxyribonucleotides
- RNA, Messenger
- RNA, Viral
- Random Allocation
- Recombinant Fusion Proteins