Article
Identification of a novel cellular cofactor for the Rev/Rex class of retroviral regulatory proteins.
Cell - 11 Aug 1995
Bogerd H P, Fridell R A, Madore S, Cullen B R
Abstract excerpt
HIV-1 Rev is the prototype of a class of retroviral regulatory proteins that induce the sequence-specific nuclear export of target RNAs. This function requires the Rev activation domain, which is believed to bind an essential cellular cofactor. We report the identification of a novel human gene p...
Topics
- Amino Acid Sequence
- Cloning, Molecular
- Gene Products, rev
- Gene Products, rex
- Molecular Sequence Data
- Mutation
- Nuclear Pore Complex Proteins
- Nuclear Proteins
- Porins
- RNA, Messenger
- RNA-Binding Proteins