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Article

HIV-1 structural gene expression requires binding of the Rev trans-activator to its RNA target sequence.

Cell - 23 Feb 1990

Malim M H, Tiley L S, McCarn D F, Rusche J R, Hauber J, Cullen B R

Abstract excerpt

Expression of human immunodeficiency virus type 1 structural proteins requires both the viral Rev trans-activator and its cis-acting RNA target sequence, the Rev response element (RRE). The RRE has been mapped to a conserved region of the HIV-1 env gene and is predicted to form a complex, highly stable RNA stem-loop structure. Site-directed mutagenesis was used to define a small subdomain of the RRE, termed...

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Source

Identifiers

PMID: 2406030
DOI: 10.1016/0092-8674(90)90670-a

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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