Article
HIV-1 structural gene expression requires binding of the Rev trans-activator to its RNA target sequence.
Cell - 23 Feb 1990
Malim M H, Tiley L S, McCarn D F, Rusche J R, Hauber J, Cullen B R
Abstract excerpt
Expression of human immunodeficiency virus type 1 structural proteins requires both the viral Rev trans-activator and its cis-acting RNA target sequence, the Rev response element (RRE). The RRE has been mapped to a conserved region of the HIV-1 env gene and is predicted to form a complex, highly...
Topics
- Animals
- Base Sequence
- Cell Line
- Cloning, Molecular
- DNA, Viral
- Gene Products, rev
- Genes, Viral
- HIV-1
- Molecular Sequence Data
- Mutation
- Nucleic Acid Conformation
- Oligonucleotide Probes