Multiple arginine residues within the basic domain of HTLV-I Rex are required for specific RNA binding and function.

doi:10.1006/viro.1993.1101

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Article

Multiple arginine residues within the basic domain of HTLV-I Rex are required for specific RNA binding and function.

Virology - 1 Mar 1993

Hammes S R, Greene W C

Abstract excerpt

The Rex protein of the type I human T-cell leukemia virus (HTLV-I) is essential for viral replication, acting post-transcriptionally to enhance the expression of unspliced and singly spliced viral mRNAs that encode the Gag, Pol, and Env virion proteins. Rex function involves its direct interactio...

Topics

Amino Acid Sequence
Animals
Arginine
Cell Line
Gene Expression
Gene Products, rex
Haplorhini
Human T-lymphotropic virus 1
Molecular Sequence Data
Mutation
RNA-Binding Proteins
Recombinant Fusion Proteins

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