Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mutational analysis of bovine leukemia virus Rex: identification of a dominant-negative inhibitor.

Journal of virology - 1 Jun 2005

Choi Eun-A, Hope Thomas J

Abstract excerpt

The Rex proteins of the delta-retroviruses act to facilitate the export of intron-containing viral RNAs. The Rex of bovine leukemia virus (BLV) is poorly characterized. To gain a better understanding of BLV Rex, we generated a reporter assay to measure BLV Rex function and used it to screen a series of point and deletion mutations. Using this approach, we were able to identify the nuclear export signal of BLV...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Active Transport, Cell Nucleus
Share to DNA, Viral
Share to Genes, Reporter

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genes, Viral

Share to HeLa Cells

Share to Leukemia Virus, Bovine

Share to Point Mutation

Share to Sequence Deletion

Source

Open in PubMed Open full text

Identifiers

PMID: 15890956
DOI: 10.1128/JVI.79.11.7172-7181.2005
PMCID: PMC1112096

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mutational analysis of bovine leukemia virus Rex: identification of a dominant-negative inhibitor.PMID 15890956Read ↗

Titration of cellular export factors, but not heteromultimerization, is the molecular mechanism of trans-dominant HTLV-1 rex mutants.Semantic proximity Read ↗

Dominant-negative mutants are clustered in a domain of the human T-cell leukemia virus type I Rex protein: implications for trans dominance.Semantic proximity Read ↗

Effects of chimeric mutants of human immunodeficiency virus type 1 Rev and human T-cell leukemia virus type I Rex on nucleolar targeting signals.Semantic proximity Read ↗

Transdominant repressors for human T-cell leukemia virus type I rex and human immunodeficiency virus type 1 rev function.Semantic proximity Read ↗

Corf, the Rev/Rex homologue of HTDV/HERV-K, encodes an arginine-rich nuclear localization signal that exerts a trans-dominant phenotype when mutated.Semantic proximity Read ↗

Multiple arginine residues within the basic domain of HTLV-I Rex are required for specific RNA binding and function.Semantic proximity Read ↗

Functional domain structure of human T-cell leukemia virus type 2 rex.Semantic proximity Read ↗

Multimer formation is not essential for nuclear export of human T-cell leukemia virus type 1 Rex trans-activator protein.Semantic proximity Read ↗

The bovine leukemia virus encapsidation signal is discontinuous and extends into the 5' end of the gag gene.Semantic proximity Read ↗

The type I human T-cell leukemia virus (HTLV-I) Rex trans-activator binds directly to the HTLV-I Rex and the type 1 human immunodeficiency virus Rev RNA response elements.Semantic proximity Read ↗

High-resolution mapping of the human T-cell leukemia virus type 1 Rex-binding element by in vitro selection.Semantic proximity Read ↗

A Bovine Herpesvirus Type 1 Mutant Virus Specifying a Carboxyl-Terminal Truncation of Glycoprotein E Is Defective in Anterograde Neuronal Transport in Rabbits and CalvesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.