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Article

Multimer formation is not essential for nuclear export of human T-cell leukemia virus type 1 Rex trans-activator protein.

Journal of virology - 1 Nov 1998

Heger P, Rosorius O, Koch C, Casari G, Grassmann R, Hauber J

Abstract excerpt

The Rex trans-regulatory protein of human T-cell leukemia virus type 1 (HTLV-1) is required for the nuclear export of incompletely spliced and unspliced viral mRNAs and is therefore essential for virus replication. Rex is a nuclear phosphoprotein that directly binds to its cis-acting Rex response element RNA target sequence and constantly shuttles between the nucleus and cytoplasm. Moreover, Rex induces nuclear...

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Identifiers

PMID: 9765406
DOI: 10.1128/JVI.72.11.8659-8668.1998
PMCID: PMC110278

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Multimer formation is not essential for nuclear export of human T-cell leukemia virus type 1 Rex trans-activator protein.PMID 9765406Read ↗

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